Criticalkare Pharma

Zytorvi 240mg Injection contains the active ingredient Toripalimab. It is a monoclonal antibody used in the treatment of metastatic or recurrent locally advanced nasopharyngeal carcinoma (NPC). It is administered as a first-line therapy in combination with cisplatin and gemcitabine for adult patients and as a single agent for those with recurrent, unresectable, or metastatic NPC that has progressed after platinum-based chemotherapy. 
Zytorvi 240mg Injection works by blocking the PD-1 receptor, preventing its interaction with the PD-L1 and PD-L2 ligands. This action lifts the inhibition on T cells, boosting their activity and enhancing immune surveillance, ultimately promoting an anti-tumor immune response. In preclinical models, PD-1 blockade demonstrated a reduction in tumor growth.
Zytorvi 240mg Injection is associated with common side effects, including nausea and vomiting, burning or tingling sensations in the feet and toes, decreased appetite, diarrhea, and constipation. It carries warnings for severe immune-mediated adverse reactions, which may affect any organ or tissue and could be fatal. These reactions can occur at any time during treatment or even after discontinuation, requiring close monitoring and immediate medical intervention when necessary. 
Also, infusion-related reactions such as hypersensitivity and anaphylaxis may occur during administration. For patients who have undergone or are undergoing allogeneic hematopoietic stem cell transplantation (HSCT), Zytorvi 240mg Injection may lead to serious complications such as graft-versus-host disease (GVHD) and other transplant-related issues. Zytorvi 240mg Injection is contraindicated during pregnancy due to the risk of fetal harm, including potential fetal death.

Uses
First-line treatment for adults with metastatic or recurrent locally advanced nasopharyngeal carcinoma (NPC) in combination with cisplatin and gemcitabine.Single-agent treatment for adults with recurrent, unresectable, or metastatic NPC that has progressed after platinum-containing chemotherapy.

Storage
Store in the original packaging to protect from moisture.Avoid direct sunlightStore Zytorvi 240mg Injection in a refrigerator at a temperature of 2°C to 8°C.Do not freeze or shake it.

Side Effects
Decreased appetiteNausea and vomitingConstipation and diarrhoeaMuscle and bone painDizzinessBurning or feeling of pins and needles in feet and toesUpper respiratory infectionSleep problemsRashFever and coughLow levels of thyroid hormoneSevere allergic reactions such as difficulty breathing, swelling of face or throatLiver problems (e.g., yellowing of skin or eyes, dark urine)Lung problems (e.g., shortness of breath, cough, chest pain)Immune system problems leading to inflammation in organsEndocrine problemsSevere infections

Bdsure 22.5mg injection consists of the active ingredient Leuprolide acetate. It belongs to the class of medicines called Gonadotropin Releasing Hormone (GnRH) agonists. This injection treats prostate cancer in men, hormone-responsive breast cancer, endometriosis (tissue that usually lines the interior of the uterus grows outside of it), and uterine fibroids (noncancerous growths of the uterus) in women. This medicine is also used for the treatment of premature puberty, which is characterized by early physical development in children due to hormonal imbalances.
Do not receive this injection if you are allergic to Bdsure 22.5mg or its ingredients, including Goserelin and Triptorlin. Before receiving this medicine, inform your physician if you have a liver or kidney impairment. Inform your doctor if you have undiagnosed abnormal uterine bleeding. Do not take this treatment if you are pregnant or planning to get pregnant. During the treatment, the existing symptoms may worsen due to the sex steroid increase in the body. Talk to your physician for more concerns. Report to your doctor if your child has a progressive brain tumor.

Uses
Prostate cancerHormone-responsive breast cancer in perimenopausal (around menopause) womenEndometriosis (a painful illness in which the tissue that normally lines the inside of the uterus grows outside of your uterus)Central precocious puberty (a child’s body begins to change into an adult too soon caused by a release of certain hormones)

Storage
Store in a cool, dry place, away from direct heat and light.Store below 25°CDo not refrigerate or freeze 

Side Effects
Severe rash, itchingShortness or difficulty of breathCough with bloodPulmonary embolismSevere headacheAltered blood sugar and cholesterol levelsInjection site reactionsLoss of appetiteAbnormal liver functionSwelling in ankle or handDifficulty sleeping, headacheMood swings, depressionWeight changesNausea, vomitingVaginal dryness, bleedingLoss of interest in sexual intercourseHot flushesBone pain, muscle weaknessBreast tenderness