Criticalkare Pharma

Caplacizumab 10 mg injection contains the active ingredient Caplacizumab, a humanized single-variable-domain immunoglobulin (nanobody) used for the treatment of acquired thrombotic thrombocytopenic purpura (aTTP).aTTP is a rare and life-threatening blood disorder characterized by the formation of small blood clots (thrombi) in small blood vessels throughout the body, leading to low platelet counts, hemolytic anemia, and potential organ damage.Caplacizumab works by targeting the von Willebrand factor (vWF) and inhibiting its interaction with platelets, thereby reducing abnormal clot formation and preventing further complications.
UsesCaplacizumab is indicated for the treatment of the following:
Acquired thrombotic thrombocytopenic purpura (aTTP)In combination with plasma exchange and immunosuppressive therapy
This therapy helps reduce the risk of thrombotic events and speeds up platelet count normalization.
Storage
Store in a refrigerator at 2°C–8°CDo not freezeKeep in original packaging to protect from lightKeep out of reach of children
Side Effects
Common side effects include:
Bleeding (nosebleeds, gum bleeding)HeadacheInjection site reactionsFatigue
Serious bleeding events may occur in rare cases and require immediate medical attention.

Xarelto 2.5mg tablet contains the active ingredient Rivaroxaban. It is an anticoagulant that belongs to the Xa inhibitors. It treats deep vein thrombosis (DVT, a blood clot present usually in the leg) and pulmonary embolism (PE, a blood clot in the lung) in adults. It also prevents DVT and PE from reoccurring after initial treatment in adults. It is also used to help prevent strokes or serious blood clots in adults who have atrial fibrillation (a condition in which the heart beats irregularly, increasing the chance of clots forming in the body and possibly causing strokes) that is not caused by heart valve disease.
Xarelto 2.5mg tablet is also indicated in children and adolescents below 18 years and with a body weight of 30kg or more to treat blood clots. It is also used to prevent the re-occurrence of blood clots in the veins or the blood vessels of the lungs, following initial treatment of at least 5 days with injectable medicines used to treat blood clots. Do not take this medicine if you are allergic to rivaroxaban or any of the other ingredients of this medicine. Do not take this medicine if you are bleeding excessively. Do not take this medicine if you have a disease or condition in an organ that increases the risk of serious bleeding.

Uses
Treatment of Stroke.Prevention of blood clots in veins after hip or knee replacement operation.Treatment of blood clots in Deep vein thrombosis, Systemic embolism and Pulmonary embolism.

Storage
Store at 25°C

Side Effects
GastroenteritisVomitingCoughFeverDecreased general strength and energyPain in the limbsHeart problemsSevere skin rashesExcessive bleeding

Xarelto 10mg tablet contains the active ingredient Rivaroxaban. It is an anticoagulant that belongs to the Xa inhibitors. It treats deep vein thrombosis (DVT, a blood clot present usually in the leg) and pulmonary embolism (PE, a blood clot in the lung) in adults. It also prevents DVT and PE from reoccurring after initial treatment in adults. It is also used to help prevent strokes or serious blood clots in adults who have atrial fibrillation (a condition in which the heart beats irregularly, increasing the chance of clots forming in the body and possibly causing strokes) that is not caused by heart valve disease.
Xarelto 10mg tablet is also indicated in children and adolescents below 18 years and with a body weight of 30kg or more to treat blood clots. It is also used to prevent the re-occurrence of blood clots in the veins or the blood vessels of the lungs, following initial treatment of at least 5 days with injectable medicines used to treat blood clots. Do not take this medicine if you are allergic to rivaroxaban or any of the other ingredients of this medicine. Do not take this medicine if you are bleeding excessively. Do not take this medicine if you have a disease or condition in an organ that increases the risk of serious bleeding.

Uses
Treatment of StrokePrevention of blood clots in veins after hip or knee replacement operation.Treatment of blood clots in Deep vein thrombosis, Systemic embolism and Pulmonary embolism

Storage
Store at 25°C

Side Effects
GastroenteritisVomitingCoughFeverDecreased general strength and energyPain in the limbsHeart problemsSevere skin rashesExcessive bleeding

Xarelto 15mg tablet contains the active ingredient Rivaroxaban. It is an anticoagulant that belongs to the Xa inhibitors. It treats deep vein thrombosis (DVT, a blood clot present usually in the leg) and pulmonary embolism (PE, a blood clot in the lung) in adults. It also prevents DVT and PE from reoccurring after initial treatment in adults. It is also used to help prevent strokes or serious blood clots in adults who have atrial fibrillation (a condition in which the heart beats irregularly, increasing the chance of clots forming in the body and possibly causing strokes) that is not caused by heart valve disease.
Xarelto 15mg tablet is also indicated in children and adolescents below 18 years and with a body weight of 30kg or more to treat blood clots. It is also used to prevent the re-occurrence of blood clots in the veins or the blood vessels of the lungs, following initial treatment of at least 5 days with injectable medicines used to treat blood clots. Do not take this medicine if you are allergic to rivaroxaban or any of the other ingredients of this medicine. Do not take this medicine if you are bleeding excessively. Do not take this medicine if you have a disease or condition in an organ that increases the risk of serious bleeding.

Uses
Treatment of StrokePrevention of blood clots in veins after hip or knee replacement operation.Treatment of blood clots in Deep vein thrombosis, Systemic embolism and Pulmonary embolism

Storage
Store at 25°C

Side Effects
GastroenteritisVomitingCoughFeverDecreased general strength and energyPain in the limbsHeart problemsSevere skin rashesExcessive bleeding

Xarelto 20mg tablet contains the active ingredient Rivaroxaban. It is an anticoagulant that belongs to the Xa inhibitors. It treats deep vein thrombosis (DVT, a blood clot present usually in the leg) and pulmonary embolism (PE, a blood clot in the lung) in adults. It also prevents DVT and PE from reoccurring after initial treatment in adults. It is also used to help prevent strokes or serious blood clots in adults who have atrial fibrillation (a condition in which the heart beats irregularly, increasing the chance of clots forming in the body and possibly causing strokes) that is not caused by heart valve disease.
Xarelto 20mg tablet is also indicated in children and adolescents below 18 years and with a body weight of 30kg or more to treat blood clots. It is also used to prevent the re-occurrence of blood clots in the veins or the blood vessels of the lungs, following initial treatment of at least 5 days with injectable medicines used to treat blood clots. Do not take this medicine if you are allergic to rivaroxaban or any of the other ingredients of this medicine. Do not take this medicine if you are bleeding excessively. Do not take this medicine if you have a disease or condition in an organ that increases the risk of serious bleeding.

Uses
Treatment of StrokePrevention of blood clots in veins after hip or knee replacement operation.Treatment of blood clots in Deep vein thrombosis, Systemic embolism and Pulmonary embolism

Storage
Store at 25°C

Side Effects
GastroenteritisVomitingCoughFeverDecreased general strength and energyPain in the limbsHeart problemsSevere skin rashesExcessive bleeding

Cytosorb device is a medical device used in critical care settings to remove inflammatory mediators from the bloodstream of patients with conditions such as sepsis, acute respiratory distress syndrome (ARDS), and cardiac surgery-associated inflammatory response syndrome (CARS). The body can produce excessive levels of cytokines in inflammation due to severe infection. This device removes these cytokine substances in your blood.
Cytosorb devices are used to treat patients aged 18 years and above with confirmed COVID-19 who are showing certain severe symptoms (including a persistent cough, high fever, developing more difficulty breathing). COVID-19 is a highly infectious disease caused by the SARS-CoV-2 virus. It is essential to inform your health care professional if you are pregnant or have any diseases or allergic conditions before starting treatment with Cytosorb devices.

Uses
Treatment of COVID-19 patients with severe symptomsAcute respiratory distress syndrome (ARDS)Cardiac surgery-associated inflammatory response syndrome (CARS)

Storage
Store at a cool temperature of 4°C and 30°C (39°F and 86°F).Do not freeze.Protected from light.Keep it in its original packaging until it is ready to be used.  
Should be disposed of properly.

Side Effects 
Very low blood pressureAbnormal heart rhythmBleedingBlood clottingLow platelet downLow levels of calcium and proteins in the bloodInfectionAllergic reactionsSepsisAnaphylactic shockHypotensionFeverDizzinessLightheadednessFainting

Tilpazan 284mg Injection 1.5 ml is a medicine containing Inclisiran as an active ingredient which belongs to the class of medications called proprotein convertase subtilisin kexin type-9 [PCSK-9]. It is first in class and only small interfering RNA (siRNA) therapy to lower low-density lipoprotein cholesterol. It is used to lower the level of low-density lipoprotein. It is prescribed as a complement to statin medication and diet in the management of patients with primary high cholesterol levels. 
It is not recommended to use this medication if you are allergic to the active compound Tilpazan Injection or its components. It is not recommended to use during pregnancy and breastfeeding; it is advised to consult your physician regarding further queries. It is not recommended for children and adolescents under the age of 18. You should be taking a statin and following a diet to reduce your cholesterol before beginning this therapy. For the duration that you are receiving Tilpazan 284mg Injection 1.5 ml, you should continue taking the statin and adhering to this cholesterol-lowering diet. Do not stop taking this medicine without consulting your doctor. Talk to your doctor if you have kidney disorders, breathing problems, liver disorders, heart problems, or intolerance to sugars before taking this medicine. Inform your physician or pharmacist of any additional medications you are taking, have recently taken, or may take, including over-the-counter medications and herbal remedies.
UsesCombination to other statin therapy and diet for treating primary hyperlipidemia [heterozygous familial hypercholesterolemia]
Storage
Tilpazan 284mg Injection 1.5 ml should be stored at room temperature, between 20°C to 25°C (68°F to 77°F).Protected from light.Keep it in its original packaging until it is ready to be used.Keep out of the reach of children and pets.Should be disposed of properly.
Side Effects
Injection site reactions like redness, rash and painArthralgiaBronchitisFeverChillsHeadache

Crenzlo 284mg Injection 1.5 ml is a medicine containing Inclisiran as an active ingredient which belongs to the class of medications called proprotein convertase subtilisin kexin type-9 [PCSK-9]. It is first in class and only small interfering RNA (siRNA) therapy to lower low-density lipoprotein cholesterol. It is used to lower the level of low-density lipoprotein. It is prescribed as a complement to statin medication and diet in the management of patients with primary high cholesterol levels. 
It is not recommended to use this medication if you are allergic to the active compound Crenzlo Injection or its components. It is not recommended to use during pregnancy and breastfeeding; it is advised to consult your physician regarding further queries. It is not recommended for children and adolescents under the age of 18. You should be taking a statin and following a diet to reduce your cholesterol before beginning this therapy. For the duration that you are receiving Crenzlo 284mg Injection 1.5 ml, you should continue taking the statin and adhering to this cholesterol-lowering diet. Do not stop taking this medicine without consulting your doctor. Talk to your doctor if you have kidney disorders, breathing problems, liver disorders, heart problems, or intolerance to sugars before taking this medicine. Inform your physician or pharmacist of any additional medications you are taking, have recently taken, or may take, including over-the-counter medications and herbal remedies.
Uses
Combination to other statin therapy and diet for treating primary hyperlipidemia [heterozygous familial hypercholesterolemia]

Storage
Crenzlo 284mg Injection 1.5 ml should be stored at room temperature, between 20°C to 25°C (68°F to 77°F).Protected from light.Keep it in its original packaging until it is ready to be used.Keep out of the reach of children and pets.Should be disposed of properly.
Side Effects
Injection site reactions like redness, rash and painArthralgiaBronchitisFeverChillsHeadache

Fragmin 2500IU Injection contains an active component as dalteparin. It is a medication used to prevent and treat blood clots. It is a type of anticoagulant, specifically a low molecular weight heparin (LMWH). This medication works by inhibiting the formation of blood clots, which can help reduce the risk of conditions like deep vein thrombosis (DVT) and pulmonary embolism. Deep vein thrombosis (DVT) is a blood clot that forms in a deep vein, usually in the legs. At the same time, pulmonary embolism is a serious condition that occurs when a clot travels to the lungs, potentially causing life-threatening complications.
Fragmin 2500IU Injection has a more predictable anticoagulant response than unfractionated heparin, allowing for easier dosing and monitoring. It has a longer half-life, which means less frequent dosing is required compared to other anticoagulants, leading to better patient compliance. Unlike warfarin, which requires frequent international normalized ratio (INR) level monitoring, this medication typically does not need such monitoring. This medication has a lower bleeding risk than other anticoagulants, making them safer for certain patient populations.

Uses
Deep vein thrombosis (DVT)Pulmonary embolism (PE)Prevention of blood clots in medical setting

Storage
Store at room temperature, between 20°C to 25°C (68°F to 77°F).

Side Effects
Signs of bleedingBlack or bloody stoolsCoughing up blood or blood clotsSevere headache or weakness, especially on one side of the bodySudden vision changesSevere abdominal or back painSevere or persistent dizziness or faintingSigns of an allergic reaction, including rash, itching, swellingBruising at the injection siteMild pain or redness at the injection siteBleeding from the gums or noseMild stomach upset or nauseaMild headacheItching or skin rash

Fragmin 10000IU Injection contains an active component as dalteparin. It is a medication used to prevent and treat blood clots. It is a type of anticoagulant, specifically a low molecular weight heparin (LMWH). This medication works by inhibiting the formation of blood clots, which can help reduce the risk of conditions like deep vein thrombosis (DVT) and pulmonary embolism. Deep vein thrombosis (DVT) is a blood clot that forms in a deep vein, usually in the legs. At the same time, pulmonary embolism is a serious condition that occurs when a clot travels to the lungs, potentially causing life-threatening complications.
Fragmin 10000IU Injection has a more predictable anticoagulant response than unfractionated heparin, allowing for easier dosing and monitoring. It has a longer half-life, which means less frequent dosing is required compared to other anticoagulants, leading to better patient compliance. Unlike warfarin, which requires frequent international normalized ratio (INR) level monitoring, this medication typically does not need such monitoring. This medication has a lower bleeding risk than other anticoagulants, making them safer for certain patient populations.

Uses
Deep vein thrombosis (DVT)Pulmonary embolism (PE)Prevention of blood clots in medical setting

Storage
Store at room temperature, between 20°C to 25°C (68°F to 77°F).

Side Effects
Signs of bleedingBlack or bloody stoolsCoughing up blood or blood clotsSevere headache or weakness, especially on one side of the bodySudden vision changesSevere abdominal or back painSevere or persistent dizziness or faintingSigns of an allergic reaction, including rash, itching, swellingBruising at the injection siteMild pain or redness at the injection siteBleeding from the gums or noseMild stomach upset or nauseaMild headacheItching or skin rash

Fragmin 10000IU Injection contains an active component as dalteparin. It is a medication used to prevent and treat blood clots. It is a type of anticoagulant, specifically a low molecular weight heparin (LMWH). This medication works by inhibiting the formation of blood clots, which can help reduce the risk of conditions like deep vein thrombosis (DVT) and pulmonary embolism. Deep vein thrombosis (DVT) is a blood clot that forms in a deep vein, usually in the legs. At the same time, pulmonary embolism is a serious condition that occurs when a clot travels to the lungs, potentially causing life-threatening complications.
Fragmin 10000IU Injection has a more predictable anticoagulant response than unfractionated heparin, allowing for easier dosing and monitoring. It has a longer half-life, which means less frequent dosing is required compared to other anticoagulants, leading to better patient compliance. Unlike warfarin, which requires frequent international normalized ratio (INR) level monitoring, this medication typically does not need such monitoring. This medication has a lower bleeding risk than other anticoagulants, making them safer for certain patient populations.

Uses
Deep vein thrombosis (DVT)Pulmonary embolism (PE)Prevention of blood clots in medical setting

Storage
Store at room temperature, between 20°C to 25°C (68°F to 77°F).

Side Effects
Signs of bleedingBlack or bloody stoolsCoughing up blood or blood clotsSevere headache or weakness, especially on one side of the bodySudden vision changesSevere abdominal or back painSevere or persistent dizziness or faintingSigns of an allergic reaction, including rash, itching, swellingBruising at the injection siteMild pain or redness at the injection siteBleeding from the gums or noseMild stomach upset or nauseaMild headacheItching or skin rash