| Packaging Type | Vial |
| Country of Origin | Made in India |
| Brand | Cladrim |
| Ingredient | Cladribine 10mg |
| Manufacturer | FRESENIUS KABI INDIA PVT LTD |
| Storage | Store Cladrim 10mg injection in a refrigerator at (2 DegreeC to 8 DegreeC). |
Cladrim 10mg injection is an antineoplastic drug belonging to the category of medicines known as purine analogues, containing the active ingredient Cladribine. It is used in the treatment of Multiple Sclerosis (is a type of autoimmune disorder that affects the nervous system). It is also used to treat Hairy cell leukaemia (cancer of white blood cells).
This drug is contraindicated in patients with current malignancies, active chronic infections like tuberculosis or hepatitis, and for those with a history of hypersensitivity reactions. High doses of this drug have been associated with the irreversible neurologic toxicity (paraparesis/quadriparesis), acute nephrotoxicity, and severe bone marrow suppression resulting in neutropenia, anaemia and thrombocytopenia. Clinicians should also monitor patients frequently for signs and symptoms of neurological impairment, such as numbness or tingling in the arms or legs, weakness, or loss of bowel or bladder control. If these symptoms occur, urgent treatment is necessary to prevent further neurological damage. It is essential to inform your doctor if you have a history of any bleeding disorders, liver or kidney disease, or if you're taking any other medications, including over-the-counter drugs, supplements, or herbal remedies.
Uses
Multiple sclerosisHairy cell leukaemia
Storage
Store Cladrim 10mg injection in a refrigerator at (2°C to 8°C).
Side Effects
Septic shock (infection throughout the body)MalignanciesAnemiaRenal failureBleedingDepressed level of consciousnessNeurotoxicityInfectionLow white blood cellsAllergic reactionsAdministration site reactionConfusion, Anxiety, InsomniaHeadache, dizzinessEye infectionAbnormal heart rateCough, abnormal breath soundsNausea, vomitingAbdominal pain, constipation, diarrheaBuildup of gasRash, itchinessChillsLoss of appetitePain, joint painFatigue, muscle weaknessSwelling in the hands and feetInflammation of vein